“Genetic ancestry testing is being applied in areas as diverse as forensics, genealogical research, immigration control, and biomedical research (1–3). Use of ancestry as a potential risk factor for disease is entrenched in clinical decision-making (4), so it is not surprising that techniques to determine genetic ancestry are increasingly deployed to identify genetic variants associated with disease and drug response (5). Recently, direct-to-consumer (DTC) personal genomics companies have used ancestry information to calculate individual risk profiles for a range of diseases and traits. [...]”
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LEE, Sandra Soo-Jin; Deborah A. BOLNICK, Troy DUSTER, Pilar OSSORIO and Kim TALLBEAR
(2009). “The illusive gold standard in genetic ancestry testing”. Science 325(5936): 38-39.